Buscopan Venus

Buscopan Venus

Manufacturer:

Opella Healthcare

Distributor:

Opella Healthcare
Concise Prescribing Info
Contents
Hyoscine-N-butylbromide 10 mg, paracetamol 500 mg
Indications/Uses
Relief from pain of stronger abdominal cramps including menstrual cramps & urinary tract spasm.
Dosage/Direction for Use
Administration
May be taken with or without food: Swallow whole w/ sufficient amount of water, do not chew.
Contraindications
Hypersensitivity. Myasthenia gravis, mechanical stenosis in the GIT, paralytical or obstructive ileus, megacolon, severe hepatocellular insufficiency (Child-Pugh C); rare hereditary conditions.
Special Precautions
Seek medical advice in case of persisting or worsening severe, unexplained abdominal pain w/ symptoms eg, fever, nausea, vomiting, changes in bowel movement, abdominal tenderness, decreased BP, fainting or blood in stool. G6PD deficiency, hepatic or renal dysfunction, Gilbert's syndrome, hepatocellular insufficiency (Child-Pugh A/B). Monitor blood count, renal & liver function after prolonged use. Discontinue use at 1st signs of hypersensitivity reaction. Avoid abrupt discontinuation after prolonged use at high doses. Not to be taken for >3 days. Patients prone to narrow-angle glaucoma, susceptible to intestinal or urinary outlet obstructions & inclined to tachyarrhythmia. Patients on controlled Na diet. Not recommended during pregnancy. Lactation. Childn <10 yr.
Adverse Reactions
Pancytopenia, agranulocytosis, thrombocytopenia, leukopenia; skin reactions, abnormal sweating, pruritus, urticaria, nausea, erythema, decreased BP including shock, anaphylactic shock, anaphylactic reactions, drug eruption, dyspnoea, hypersensitivity, angioedema, rash, exanthema; tachycardia; bronchospasm; dry mouth; increased transaminases; urinary retention. Paracetamol: SJS, TEN, acute generalized exanthematous pustulosis.
Drug Interactions
Hypnotics & antiepileptics (eg, glutethimide, phenobarb, phenytoin, carbamazepine); rifampicin; potentially hepatotoxic substances & alcohol. Intensified anticholinergic effects of tri- & tetracyclic antidepressants, antihistamines, antipsychotics, quinidine, amantadine, disopyramide & other anticholinergics (eg, tiotropium, ipratropium, atropine-like compd). Diminution of the effects of both drugs on GIT w/ dopamine antagonists eg, metoclopramide. Enhanced tachycardic effects of β-adrenergic agents. Paracetamol: Long-term use w/ oral anticoagulants. Enhanced tendency of neutropenia w/ zidovudine. Concomitant use w/ probenecid. Reduced absorption w/ cholestyramine.
MIMS Class
Antispasmodics / Analgesics (Non-Opioid) & Antipyretics
ATC Classification
A03DB04 - butylscopolamine and analgesics ; Belongs to the class of belladonna and derivatives antispasmodics in combination with analgesics. Used in the treatment of functional gastrointestinal disorders.
Presentation/Packing
Form
Buscopan Venus FC tab
Packing/Price
100's (P3,125/box);4's (P119/box)
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